Health Benefits and Uses of Asiatic Pennywort (Gotu Kola)

High Blood Pressure:

Research has linked Gotu Kola with a decrease in many diseases like congestive heart failure, and one of the positive associations with the herb was blood pressure. Gotu Kola is able to regulate blood pressure and reduce strain on the cardiovascular system by relieving anxiety and tension in the arteries and blood vessels. This protects the heart and prevents diseases like heart attacks, stroke, and atherosclerosis from occurring.

Blood Circulation:

Gotu Kola actually plays two important roles in the circulatory system, both of which benefit our bodies. Firstly, the plant extract can protect and strengthen the walls of blood vessels and capillaries, which prevents blood leakage and optimizes the circulatory system. Secondly, it stimulates the flow of blood, which increases oxygenation in different parts of the body and important organ systems. This also alleviates problems caused due to poor blood circulation such as swelling, leg heaviness, and pain. The strengthened blood vessels and capillaries aids in accomplishing proper blood circulation, and in turn reduce the chances of thrombosis as well as regulate the blood pressure. This also diminishes the risk of heart attack, stroke, and atherosclerosis.

These effects are believed to be linked to chemical compounds known as triterpenes, which stimulate the production of cardiac glycosides. Cardiac glycosides are organic compounds that increase the force of the heart and increase the rate of the heart's contractions. There is some evidence that Gotu Kola may stabilize fatty plaques in blood vessels, preventing them from breaking off. This is important because maintaining optimal brain circulation is one of the most important things you can do to keep your brain healthy and fit.

Blood Clotting:

Centellase, a chemical compound found in Gotu Kola, has been found to help reduce swelling and improve circulation in the legs of people suffering from circulation problems. Gotu Kola protects and strengthens the walls of blood vessels and capillaries while stimulating blood flow. It optimizes the circulatory system and provides oxygen to various parts of the body to prevent swelling, heaviness in the feet and pain. It prevents blood clotting. Because of this, it is also believed that Gotu Kola can help with reducing blood clots, but more research needs to be done in order to confirm this claim.

Cardiovascular Diseases:

Centella asiatica has a positive effect on cardiovascular diseases. The main components that affect the cardiovascular system are asiaticoside and asiatic acid. hypertension and atherosclerosis are the mostly studied diseases in involved articles.

Mix the ingredients: Centella leaves, Walnut, Badam, Cardamom, Pepper. Powder it and eat it with sugar candy on early mornings will cure the severity of heart diseases.

Hypertension:

Hypoxic pulmonary hypertension can cause pulmonary arterial changes, including pulmonary arterial stiffness and narrowing. Ventricular changes caused by right ventricular hypertrophy and right ventricular fibrosis affect ventricular function. Renovascular hypertension is one of the common causes of secondary hypertension. About 90% of cases are due to atherosclerotic renal artery stenosis and often accompanied by severe occlusive diseases of other blood vessels, accounting for poor prognosis. The Ang II/AT1R signaling pathway can regulate a series of intracellular pathways to improve cardiac insufficiency and myocardial remodeling, which is closely associated with the occurrence and development of renal hypertension. The transverse aortic constriction contributes to the occurrence of cardiac hypertrophy and failure. The common pathological changes are systolic dysfunction and cardiac fibrosis of the heart. Pressure overload triggers the expression of inflammation genes. Inhibiting early inflammation reactions can reduce cardiac remodeling and improve heart function.

Fibrosis:

Fibrosis is a pivotal player in the development and progression of heart failure, which is controlled by the TGF-β/Smads pathway. Smad2 and Smad3 are the two main downstream regulators of TGF-β1-mediated tissue fibrosis, and Smad7 is a negative feedback regulator. Cardiovascular diseases can cause a variety of pathological changes and affect the development of related pathology by affecting Ang II/AT1R and TGF-β/Smads signaling pathways.

Atherosclerosis:

Atherosclerosis is a disease in which the inside of arteries narrows due to the buildup of plaque, leading to some serious problems such as heart attack, stroke, or even death. Maintaining arterial integrity and retaining endothelial barrier function and normal contraction of smooth muscle can limit the development of atherosclerotic disease. Asiaticoside has been found to reduce endothelial permeability; it can effectively protect the occurrence of atherosclerosis by lowering the levels of intercellular adhesion molecule-1, vascular cell adhesion molecule-1, and E-selectin. Moreover, it can also reduce the levels of related inflammation factor (IL-18) and has anti-inflammation effects. A cell experiment found that asiatic acid reduced atherosclerosis by inhibiting the redistribution of occludin and zona occludens -1(ZO-1). Furthermore, it decreased F-actin rearrangement and myosin light chain dephosphorylation.

Myocardial Ischemic Disease:

In myocardial ischemic disease, apoptosis is the main cause of cardiomyocyte death and asiatic acid could reduce the levels of apoptotic factors (Bax/Bcl-2, caspase-9, caspase-3) and improve cardiomyocyte apoptosis. It can also improve the fibrotic changes caused by myocardial dysfunction by affecting the TGF-b1-Smad2/3 signaling pathway. In addition,

Arterial Plaques:

Arterial plaques are associated with atherosclerosis, coronary artery disease (CAD), and heart disease in general. When arterial plaques are structurally weak, they are more likely to rupture and cause embolism (artery obstruction/clotting). It has been proposed that a terpenoid extract in this plant may help to stabilize arterial plaque structure by increasing collagen composition. This might decrease the risk for plaque rupturing and subsequent embolisms.

Carotid and Femoral Plaques:

Carotid artery plaques that are echolucent on ultrasound have greater amounts of certain physiological components (e.g., lipids, blood elements) and limited amounts of collagen, making plaque inherently weaker and increasing the risk of embolization. This unstable plaque is associated with a higher clinical risk of stroke and asymptomatic cerebral lesions.

Platelet Aggregation Inhibition:

Thrombosis:

Gotu kola helps prevents blood clotting and as a herbal remedy may aid in alleviating the symptoms of thrombosis, which is defined as blood clotting in the blood vessels.

People who have low to medium rate venous disease in varicose veins were directed to add Pennywort in their daily routine for two days before the flight, on flight day, and a day after the flight. They found relatively less fluid retention and ankle swelling that skipped Pennywort. Pennywort can improve microcirculation in veins and arteries, protect arteries’ inner armor and improve the elasticity of veins. With this ability, Pennywort is often used to treat arteries’ hypertension in lower limbs. Gotu Kola is known to support healthy veins and vessels throughout the circulatory system. The most common problems due to degeneration or malfunction of blood circulation are varicose veins and haemorrhoids. When the extract of Gotu Kola leaves is consumed, triterpenes a molecule of Pennywort  works on the veins, improving their tone and making them less susceptible to the degenerative processes that can lead to varicose veins and other problems.

Many lab studies and research have shown that Pennywort can be highly helpful in treating varicose veins. The reason is, Pennywort on the connective tissue of the vascular wall can impose positive metabolic effects. Whether you have varicose veins or experience ankle swelling after a flight, you'll be happy to learn that Pennywort is thought to reduce ankle swelling.

Blood Vessels:

Gotu Kola strengthens the vein and maintains the connective tissue functioning by stimulating the formation of chondroitin sulfate and hyaluronidase.

Venous Insufficiency:

When blood vessels lose their elasticity, blood pools in the legs and fluid leaks out of the blood vessels. That causes the legs to swell (venous insufficiency). Several small studies suggest Gotu Kola may help reduce swelling and improve blood flow. Asiaticoside and madecassoside are two triterpenoid saponin compounds found in Gotu Kola. It is thought that these constituents may be responsible for the benefits to wound healing and venous insufficiency as they have been seen to have anti-inflammatory effects. Gotu Kola also seems to increase release of an inflammation mediator called IL-6 (interleukin-6).

Researchers think this might be responsible for the positive effects on venous insufficiency. BuUpregulated IL-6 release may also cause the antirheumatic effects proposed for this supplement. This herb may slow down activities of a group of enzymes that break down collagen, the primary structural protein found in skin and connective tissues. It also seems to simultaneously increase the rate that collagen is synthesized. A terpenoid extract from this plant improved remodeling in connective tissue in animal models. This is linked to increase activity of fibroblasts, increased epithelial turnover, decreased capillary permeability, and greater collagen synthesis.

Chronic Venous Insufficiency (CVI):

Venous insufficiency refers to inadequate blood flow through veins. This condition often results from dysfunction in the veins or one-way vein valves in the legs. Blood pools in the legs unable to return to the heart for pumping and can cause symptoms like burning, aching, pain, stinging, and swelling. One possible cause of venous insufficiency is loss of elasticity in blood vessels.

There is some evidence that Gotu Kola can improve blood circulation in people with Chronic Venous Insufficiency. CVI is a condition that presents when the valves or walls in our leg veins are not healthy and causes difficulties in circulating blood to the heart. Several clinical studies have suggested that Gotu Kola can improve blood flow and reduce swelling in people with chronic venous insufficiency, relative to placebo controls.

If you are interested in learning more about Centella asiatica it is recommended that you speak with your doctor to determine if this supplement is right for your needs.

Varicose Veins:

Varicose veins is a condition where veins swell up in the legs and feet, thereby obstructing the smooth flow of blood across organs and tissues. Gotu Kola, being rich in iron, has the potential to remove plaques from blood vessels, and thus regulates blood pressure and heals varicose veins. Several studies have suggested that gotu kola may be used to treat varicose veins and venous insufficiency.

Venous Hypertensive Angiopathy:

The NMCD rates Gotu Kola as possibly effective for venous insufficiency. This means that preliminary research shows that it works, but more studies are needed to determine efficacy for all people. There have been some promising results seen in studies using Centalla asiatica for atherosclerosis (Arterial Plaque Buildup), cognitive function, deep vein thrombosis, keloid scars, general scarring, stretch marks, and wound healing. Despite the long history of use of this plant in traditional medicine, human research is quite limited. More clinical research is needed to determine the therapeutic efficacy of Gotu Kola for these and other conditions. Centella asiatica products are available as dietary supplements in the United States. The FDA has not approved Gotu Kola as a drug to prevent or treat any medical conditions.

Regular use of Gotu Kola is a natural way to get rid of the inflammation of the tissues around the teeth, often causing shrinkage of the gums and loosening of the teeth. It helps to improve overall dental health. Research has proven that extracts of Gotu Kola and pomegranate improves clinical symptoms of chronic periodontitis.

Removes Stains on Teeth:

Powder of Asiatic Pennywort can be used as tooth powder that removes stains on teeth and strengthens the gums.

Periodontal Healing:

Rheumatoid Arthritis (RA):

Animal and cell experiments confirmed that madecassoside exerted an anti-rheumatoid effect. Rheumatoid arthritis is a chronic inflammatory joint disease that usually affects women and elderly people; the main pathological change is persistent synovitis. If not controlled well, it can lead to joint deformities and other diseases and decrease patients’ quality of life.

In summary, madecassoside as a triterpene component of Centella asiatica, may have anti-arthritis effect, and the underlying mechanism is reduction in the level of inflammatory factors.

Osteoporosis:

Osteoporosis is a bone metabolism disease, manifesting itself in the form of bone loss and structure degradation. Main targets are the middle-aged and elderly people over the age of 50. The occurrence of osteoporosis can be linked to other endocrine morbidities, like diabetes, obesity, thyroid hormone disease.

One of the more traditional uses for Gotu Kola is to use the extract topically. Gotu Kola has the ability to help replenish the skin by promoting collagen synthesis which helps keep the skin supple, firm, and above all, strong. This is why traditionally Gotu Kola was employed extensively to help promote healthy wound healing. These effects may extend to oral supplementation too, helping to optimize skin health from within. The only way this can be achieved, however, is to protect the triterpenes from our stomach acid as it degrades the main triterpene compounds responsible for enhancing skin health. This is why topical Gotu Kola works well for optimizing skin health as it is not degraded by stomach acid. As we discussed earlier, our innovative enteric coated Gotu Kola tablets help to preserve these delicate triterpene compounds, which allows them to exert their positive effects on our skin.

Since ancient times, it is used to treat many skin-related disorders such as eczema, erysipelas, leprosy, psoriasis, and eczema. Not only this, there are many cosmetic companies, which are interested in using this herb because of its facial beauty benefits. Gotu kola along with treating cellulite is used for all skin problems from acne to wrinkles. Gotu Kola increases the collagen production in the skin so it prevents skin aging and maintains the youthfulness of the skin. Gotu Kola when taken internally treats acne and when Gotu Kola oil is applied externally, it treats acne scars too. Gotu Kola also firms up the skin and prevents skin wrinkles. Gotu kola extract also can be used as a massage oil to treat and prevent stretch marks. Gotu Kola oil is also used to treat minor burns and most of the skin infections. Since Gotu Kola has been proven without doubt that it is very effective for treating all the skin problems, Gotu Kola based creams are widely available now. Try either the Gotu Kola cream or oil for external application and Gotu Kola tea for internal consumption. The plant’s richness in antioxidants and its saponins can improve and reduce the appearance of scars, blemishes, and wrinkles. It also prevents the accumulation of scar tissue, thereby keeping your skin beautiful even after an injury. Gotu Kola is a sought-after herb by cosmetic and pharmaceutical companies. With the saponins, this herb has the ability to treat various skin conditions like acne, dermatitis, and psoriasis. Topically it can heal skin ulcers and reduce wrinkles, lighten blemishes, delay signs of ageing and improve the varna or quality of the skin.

Some studies also suggest that the use of Gotu Kola or its components may be useful in the treatment of scleroderma. Gotu Kola is a common ingredient of cosmetics applied to skin photoaging also in cellulite and striae.

"The anti-inflammatory properties increase hydration and help soothe and repair dry, red, irritated skin", explains Shari Marchbein, MD, a dermatologist in New York City. That's why it's recommended for treating various skin conditions, especially those with symptoms such as redness and roughness (think psoriasis and eczema). Chiara Butler, a chemist at Function of Beauty, the brand's new manufacturers skin-care line utilizes the ingredient in some of its products, says two skin-beneficial compounds in the plant's chemical makeup are madecassoside and asiaticoside, both known for their soothing properties. "Cica also boosts circulation and has been shown to increase collagen production, improving skin firmness and elasticity", points out Dr. Marchbein.

To get rid of the above-said skin problems, it is recommended that one should use externally the powder of Gotu Kola and vaseline both in the morning and evening. The application of its extract helps to reduce skin scars. Its cream helps to reduce scarring. It is helpful to minimize pregnancy marks if the mix of Gotu Kola and vitamin E starts applying for about 6 months.

Used in Cosmetics:

Pennywort is cold and full of nutritious that is useful in beauty care also. The herb juice is a natural moisturizer for the skin, slowing down aging, removing scars, and stretch marks. It is also suitable for acne. Saponins found in Gotu Kola are mainly adept at improving the appearance of the skin. Many cosmetic and pharmaceutical companies are concerned in it because of its ability to reduce the appearance of scars, wrinkles, and other blemishes. It prevents the accumulation of scar tissue, which helps to keep your skin beautiful, even after an injury or a surgery. This antioxidant activity to reduce signs of aging is one of the reasons gotu kola is becoming so popular in the west. Gotu Kola is known among cosmetic and pharmaceutical companies for its ability to keep the skin beautiful, reduce signs of aging, scars, and blemishes. This ability of the plant is related to its high content of antioxidants and saponins. This plant can also be used to cure Psoriasis, a hyperproliferative skin disorder.

Centella asiatica is loaded with a plethora of favorable properties. It is a rich source of amino acids, beta carotene, fatty acids, and many potent phytochemicals. Due to these properties, Centella asiatica is not only an acceptable ingredient for your overall wellness but can also be very beneficial to the health of your skin. Many cosmetic manufacturers incorporate Centella asiatica extracts in their skincare products, often labeled "cica creams".

Protection From UV Rays:

Anti Aging:

Extracts of Centella asiatica can combat the signs of aging. It helps the skin to rejuvenate itself and fights against photo-induced aging. Its fluid retention properties trap moisture in the dermal layers and make the skin appear more plump and young. Higher moisture content in the skin cells reduces wrinkles and erases fine lines from the skin. Centella Asiatica contains a lot of flavonoids and an active compound called Madecassoside, which serves as antioxidants that help neutralize the free radical damage caused by the sun and pollution exposure. They also improve blood circulation and the synthesis of collagen and skin tissue for maintaining a youthful complexion. Collagen also plays a key role to enhance skin elasticity and reduce the signs of aging like wrinkles and fine lines. Due to this ability of CA to increase collagen (type I & III) production, research suggests that it can have anti-ageing capabilities and can be used in treating photoageing skin as well. It can help the skin retain a plump and youthful appearance.

You can work the plant extract into almost any step of your skin-care routine, it’s incorporated into cleansers, toners, serums, and creams. “I like creams and serums because they sit on the skin for a long time for maximum efficacy”, says Nikita Wilson, a cosmetic chemist in New York City. Butler agrees, adding that a cica cream can be used either morning or night, or both. (It’s worth noting that Centella asiatica products are often spiked with a green tint to counteract the redness that comes with an inflamed complexion). It is recommends applying a "cica balm" on top of your retinoid in the p.m. because while retinoids can aggravate skin, the cica will prevent irritation. Things like pollution, cigarette smoke, alcohol, and radiation expose our bodies to things called free radicals, which have been shown to speed up aging and cause illness. But antioxidants, which Gotu Kola contains in spades, are thought to help neutralize the risk. "Gotu Kola's antioxidant properties help us fight signs of aging", says Sanders, who adds that it may even be used to reduce the appearance of cellulite and stretch marks.

Rejuvenation:

Regular use of this herb helps in slowing down aging process. Its anti aging properties help to rejuvenate body tissues and boosts body immunity. Lactating mothers can reap the benefits of this herb, as it increases milk secretion and also purifies it. Apart from these benefits the herb Gotu Kola also acts as an antipyretic. It helps to reduce fever and normalize body temperature. This herb may cause headache, rashes and giddiness when used in excess.

Moisturizing Skin:

Centella asiatica is rich in amino acids, beta carotene, fatty acids, and phytochemicals, which provide powerful nutrients for the skin. Amino acids is a great hydrating ingredient to soothe rough and irritated skin.

Soothing:

The main active constituents of Centella asiatica are saponins known as asiaticosides, which have soothing and healing properties. One of the main reasons that so many companies use Centella for stretch marks is that it acts as a soothing agent to damaged skin. These constituents have powerful healing properties, which means they can calm irritated, pained skin. Gotu Kola has shown to reduce skin irritation, it is ideal to restore your skin’s moisture barrier so it can protect itself from breaking down even more, especially for sensitive skin which is red, inflamed, irritated or itchy. It helps reduce the visible signs of skin sensitivity such as itching and burning significantly. This is one of the reasons why it’s used in products for people with sensitive and acneic skin. It speeds healing, improves overall acne severity and prevents future blemishes and scarring. More benefits of the Centella asiatica extract include: antioxidant-boosting effects, antibacterial properties, hydration and reduced transepidermal water loss, as well as photoprotection.

First of all, it’s excellent for sensitive skin, and you don’t run the risk of it causing irritation, as so many other skincare products do. Second of all, because of these asiaticosides, Centella helps relieve itchiness, which can be frustrating and intense, especially when the stretch marks are new.

Hydrating:

Gotu Kola can be good for those which use medication or ingredients that can be drying to the skin, like acne-fighting products, to not only soothe inflamation, but hydrate the dry areas, too. Other than products labeled as Centella asiatica or "Cica", you may have also noticed skin care formulated with only madecassoside. Madecassoside is a very popular ingredient for acne-prone skin because it controls inflamation and stimulates production of type III collagen, which is the second most abundant collagen in human tissues (whereas asiaticoside stimulates type I collagen).

So, to sum up the benefits Gotu Kola extract could have when applied to skin: combats and reduces inflammation, speeds wound healing and recovery, improves circulation, boosts collagen, hydrates, increased skin resilience, antioxidant-boosting effects, antibacterial properties, and pigment-fading and photoprotection.

Stretch Marks:

Gotu kola is rich in antioxidants and contains saponins which improve the appearance of the skin. Many cosmetic and pharmaceutical companies are interested in it because of its ability to reduce the appearance of scars, wrinkles, and other blemishes. According to research, Gotu Kola is also effective in the treatment of wounds, burns, and hypertrophic scars. Gotu Kola has rich amounts of terpenoids, which can significantly increase collagen synthesis in your body. It, in turn, can reduce existing stretch marks and prevent new stretch marks from showing up. Research has suggested that applying Gotu Kola extract on the skin can prevent stretch marks from growing and lighten their scars. This ingredient is already added to many skincare products, like serums, balms, cleansers, toners, and creams. You can, therefore, just go on with your standard regimen. Just check the ingredients before purchasing your products. Centella asiatica can be applied to the skin in the day or night. Or both. Gotu Kola can be helpful for older streaks, as well. By encouraging new skin layers to emerge, your stretch marks will begin to appear less and less severe. However, we make a point of recommending early treatment (ideally when the marks are still colored), to get the best result.

Gotu Kola is loaded with anti-inflammatory properties as well as antioxidants. It contains two compounds called madecassoside and asiaticoside, known to soothe the skin. The former is an antioxidant that protects your skin from damage caused by free radicals. It's excellent at soothing dryness, redness, roughness, inflammation and hydrating the skin. This is why it can treat symptoms of conditions like eczema and psoriasis. It's also known to boost circulation for a youthful appearance and increase collagen production to firm the skin, reduce the visibility of wrinkles and lines, and improve elasticity. According to research, this ingredient can mitigate the effects of damage caused by exposure to the sun and revitalise the skin's protective barrier. And it has healing properties, prevents scarring, and strengthens the skin. Notice how the plant addresses most skin-related concerns and skin types, sensitive, dry, dull, and mature.

There are two specific multi-ingredient cream formulations (trofolastin and verum) containing Centella asiatica that have been observed to reduce the formation of stretch marks during pregnancy. Another topical cream product containing Centella asiatica triterpenes applied twice daily beginning at 10-14 weeks pregnant till the end of pregnancy has been observed to decrease the severity of both new and old stretch marks and the incidence of new stretch marks. These creams also contain other ingredients such as rosehip oil, vitamin E, elastin, and essential fatty acids. The effect of Gotu Kola alone is not known and more research is needed. Preliminary evidence suggests that using a skin cream called Alpha centella two times a day for 6 – 8 weeks might reduce scarring after removal of surgical sutures. This was noted in patients after receiving surgeries to remove excessive scar tissue formations called keloids. More research is needed to determine how gotu kola affects wound healing, scarring, stretch marks, and other dermatological conditions.

Something we find impressive about Centella asiatica is that it is supported by an abundance of clinical trials and studies. You see, we regularly hear about natural ingredients that may or may not be beneficial for stretch marks, but few are actually supported by evidence. Some studies suggested that the terpenoids found in Gotu Kola may help increase collagen production in the body, which may help prevent new stretch marks from forming and reduce the appearance of existing marks. However, it is advisable to do a patch test before using any topical medication.

Use a topical cream that includes 1% Gotu Kola extract. Apply it to affected areas several times a day for better results.

Skin Diseases:

The Centella asiatica extract and its triterpenoids had certain therapeutic and relieving effects on acne, baldness, vitiligo, atopic dermatitis, and wounds. Acne is one of the most common skin disorders. Studies have pointed out that the activation of vascular endothelial cells and the involvement of inflammation responses are essential for the early stages of the development of acne lesions. Vitiligo is an acquired depigmenting disorder of the skin, and one of the most common skin diseases. Some studies suggested that oxidative stress may be the initial cause of this disease. The main targets of ROS are mitochondria, causing structural and functional changes. Atopic dermatitis, also known as atopic eczema, is a chronic relapsing inflammatory skin condition. This disease occurs due to skin barrier dysfunction, alterations in cell-mediated immune responses, and Immunoglobulin E(IgE)-mediated hypersensitivity. Skin is the largest organ of the human body playing a vital role in maintaining the body’s physiological homeostasis. The appearance of wounds can lead to an imbalance in physiological homeostasis. The stages of wound healing comprise inflammation, proliferation, epithelialization, angiogenesis, remodeling, and scarring.

For wound healing, the present study found that Centella asiatica and its triterpenoids had a direct wound-healing function. Centella asiatica extracted with methanol contains 0.12% asiatic acid, 0.54% madecassic acid, 0.25% asiaticoside and 1.02% madecassoside, and was made into a spray with hydroxypropyl-β-cyclodextrin, Eudragit E100, glycerin, PEG 400, etc., and the spray of triterpenes content are close to 100% compared with Centella asiatica extract, the wound was healed completely without any skin irritation. Compared with ordinary gauze, the electrospun gelatin membranes containing Centella asiatica can promote the wound repair process by affecting the proliferation of fibroblasts and collagen synthesis, and are antibacterial as well. The asiaticoside-rich hydrogel formulation exhibited 40% fast wound healing without any skin irritation as compared to untreated group. Thick epithelial layer and keratin formation can be found, while granulation tissue, fibroblasts and collagen were formed moderately. Cells studies have found that Centella asiatica standard extract (ECa 233) can affect the formation of filopodia and promote wound healing by activating the FAK, Akt and MAPK signaling pathways. In above studies, though the vehicles were different, but animal and cell experiments have found that Centella asiatica and its triterpenoids improved the degree of re-epithelialization, increased the collagen synthesis, reduced the inflammation around wounds and cause no obvious skin irritation.

For the treatment of atopic dermatitis, Centella asiatica significantly reduced the inflammation response (TNF-α ↓, IL-1β ↓, IL-8 ↓, IL-4 ↓, and IL-13 ↓), and also the local immune response (IgE ↓). Whether titrated extract of Centella asiatica or ethanol extract of Centella asiatica, both seems to inhibit hyperkeratosis, mast cell and inflammatory cell infiltration. Both of them can inhibit the expression of iNOS and COX-2 and NF -κB activity, it confirms that Centella asiatica extract may be a promising therapeutic for the treatment of atopic dermatitis. The effect of madecassoside in the treatment of dermatitis is reflected in reducing the pro-inflammatory cytokines (IL-1β, TLR2), moreover, it can promote the secretion of AQP3, LOR, IVL in HaCaT keratinocytes and the secretion of HA in human skin fibroblasts, thus can significantly enhance skin hydration.

Madecassoside, a specific component of Centella asiatica, had a certain improvement effect on vitiligo, and the possible mechanism of action was to reduce the oxidative stress response and weaken the damage to mitochondria by oxidative stress [matrix metalloproteinase (MMP) ↑ and [Ca2+]i ↓]. In addition, it was found that the LC3-II/LC3-I ratio of melanocytes treated with madecassoside increased significantly, suggesting that it enhances the autophagy activation of the cells, thereby protecting skin cells from physiological and pathological aging damage. Lastly, Centella asiatica also demonstrated a positive activation effect on dermal papilla, improved the viability of dermal papilla cells and increased the expression of characteristic genes related to hair growth in the cells, thus providing good application prospects for baldness.

Although Centella asiatica and its triterpenoids have low transdermal absorption rate, current animal experiments and cell experiments have found that they can effectively promote wound healing, reduce skin inflammatory diseases, and seem to have a certain effect on vitiligo and baldness. The mechanism of action of Centella asiatica and its ingredients in the treatment of skin diseases is mainly anti-inflammation, anti-oxidation, and weakening of the damage to mitochondria by oxidative stress, which was consistent with the pathogenesis of these diseases.

¼ of soaked rice ground with Gotu Kola leaves and can be added Onions and Rotis are made. This herbal roti cures skin diseases.  

Psoriasis:

Your skin is the largest organ of your body which plays essential roles like generating vitamin D, preventing dehydration, and maintaining your body temperature. It’s also constantly exposed to the elements and to bacteria, which makes it prone to infection and inflammation. One common skin condition is psoriasis. Data shows that 125 million people. Gotu Kola can inhibit skin cell reproduction. Although not potent, it can be used as an herbal aid in providing relief from symptoms of psoriasis, which is a hyperproliferative skin disorder.

It is the best remedy for skin diseases like eczema and psoriasis. Boil Centella leaves with cow ghee and make it cool and apply on the skin.

Scars:

Oral and topical use have reported benefits on wound and scar management with relief of symptoms, disappearance of inflammation and hastening of scar maturity.

Wounds, Burns and Injuries:

As kids, we are always falling and covered in bruises and wounds. What our elders would do is take a bunch of Gotu Kola leaves, moisten the herb with saliva chew it for a while. With chewing it becomes dark green in colour. This is then taken out and applied on the wound with a bandage wrapped around it. The bandage is left for a day. Depending on the intensity of the wound, the dressing is changed. Gotu Kola has long been used traditionally in many civilizations to heal wounds, both internally and topically. Once famous for its use in treating leprosy in India, in Ayurveda, Gotu Kola is used today by herbalists to treat burns, minimize scarring, heal wounds, and promote tissue repair after injury or surgery. It appears to promote wound healing through its anti-inflammatory, antioxidant, and antibacterial qualities, in addition to stimulating keratinization (an integral process of nail and hair growth) and epidermal repair (the epidermis is the outermost layer of the skin). The main component asiaticoside helps in increasing type 1 collagen formation and angiogenesis thus heals wound rapidly. These compounds also inhibit inflammatory and improve capillary permeability.  Its use is recommended in open sores and chronic wounds. A set of lab studies and medical records showed that the Gotu Kola extract could regenerate connective tissues to generate new skin and stimulate biological processes in cell division to heal wounds rapidly.

In Asia, people often call Centella asiatica "tiger grass", believing that injured tigers roll in the herb because of its healing properties. Several reports offer evidence for these allegedly magical effects. Gotu Kola has another benefit in this healing arena: Its adaptogen-like qualities help with the emotional and physiological stresses of physical trauma. Calendula flowers (Calendula officinalis) also promote tissue repair and support the lymphatic system in fighting infection, so I frequently pair them with Gotu Kola. Along with Gotu Kola’s wound healing properties, it’s also applied topically to mollify a variety of skin conditions, including insect bites, seborrheic dermatitis, cold sores, eczema, psoriasis, and dry, irritated skin. I like to infuse the dry herb into sesame or coconut oil, which can be rubbed into the scalp to calm the mind, deepen sleep, and promote hair growth.

You can find Gotu Kola in many creams for wound healing. Ask your health care provider if one is right for you. Apply an ointment that contains 1% Gotu kola extract on wounds several times a day. In addition to its internal use in healing injuries, Gotu Kola is used topically, in the form of poultices, compresses, soaks, and infused oils (don’t use infused oils on fresh burns). A compress is the simplest preparation: prepare a concentrated tea, strain it, and soak a clean washcloth in the tea when it’s still warm. Apply the cloth to the affected area several times per day. The proportions of tea to water aren’t essential for this herb, simply make the tea about three times as strong as you would make a tea to drink.

TECA, the titrated extract of Centella asiatica is a reconstituted mixture of three triterpenes extracted from the plant. Used extensive in Europe as a wound healing drug, it has been shown to stimulate collagen synthesis and increase tissue tensile strength. It has been found successful in the treatment of burns, scars and wound healing defects.

Cellulite:

Cellulite is one big problem that every women faces and almost 90 to 95% of the women have cellulite. Because it affects almost all the women, the market for selling anti cellulite medicines, creams and lotions are also big. Every year millions are spent on anti cellulite creams and treatments but very few have been proven to be effective. Out of the few, Gotu Kola stands out for it’s use in reducing cellulite as it has been proven through research that it is very effective for reducing cellulite.

You can either consume in the form of tablets or in powder form. Finally we have scientific proof that a herb does reduce cellulite.

Scleroderma:

Packed with nutrients that promote oxygen supply to the brain, Gotu Kola is very beneficial in decreasing levels of stress, anxiety and depression. It also has mild sedative properties and is hence useful for those suffering from insomnia and other sleep disorders. Gotu Kola increases levels of the feel-good neurotransmitters serotonin, dopamine, and norepinephrine, and reduces levels of the stress hormone cortisol. Additionally, Gotu Kola protects the brain from inflammation. Chronic inflammation of the brain is now thought to be an underlying cause of depression.

Stress:

Stress is becoming a common factor in the present age with a hectic lifestyle, and daily pressure in different forms. Stress can lead to sleep deprivation, the result of which is anxiety. Gotu Kola has immense therapeutic potential. The herb has a positive effect on anxiety issues. It calms the adrenal glands, which in turn lowers the release of stress hormone and increases dopamine and serotonin levels.

One of the Gotu Kola benefits is in its powerful stress relieving abilities. It raises the levels of the “feel good” neurotransmitters dopamine and serotonin, and lowers levels of the stress hormone cortisol. It can eliminate anxiety, depression, mental fatigue, and insomnia. A wonderful Ayurvedic remedy for stress disorders.

Research findings have found that Gotu Kola extract may help regulate stress levels by positively influencing the calming areas of the brain. These calming brain regions respond to a relaxing neurotransmitter called GABA and Gotu Kola has a gentle yet prominently positive influence of GABA signaling. This has been found to regulate tension related to stress which helps keep us level headed during abnormal periods of stress.

Acute and Chronic Stress:

Gotu Kola can lower acute and chronic stress. It imposes calmness and alertness into our mind and body by 100%. There are many scientific research and lab studies that showed Gotu Kola could be used to treat anxiety symptoms as it can reduce the reactions of the acoustic startle reflex, which is considered the main sign that a person is in heavy mental stress.

Anxiety:

Gotu Kola is a natural anxiety reliever. Centella asiatica also has anxiolytic properties. The components madecassoside and asiaticoside possess anxiolytic activity. These compounds help in the treatment of both acute and chronic anxiety in the pathological state. It can have a positive effect on anxiety issues as it lowers the stress hormone, cortisol, and increases serotonin and dopamine levels. It effectively decreases the frequency and severity of anxiety attacks and episodes in a group of subjects who suffered from some form of General Anxiety Disorder (GAD). The anti-inflammatory properties of this herb can lower the signs of depression and despair. It is also known to enhance spirituality, thus, sometimes referred to as the "Herb of Enlightenment". Very little scientific evidence suggests that Gotu Kola may help reduce anxiety. Although the exact chemical pathways are still being researched, there is significant evidence that Gotu Kola can have a positive effect on anxiety issues for a broad range of patients. Research has revealed that it reduced the frequency and harshness of anxiety attacks and episodes in a group of subjects who suffered from some form of GAD. Based on a test on a group of people who suffer from a form of GAD, the use of Gotu Kola benefits the body by decreasing the occurrence and seriousness of anxiety episodes.

This herb has been studied for anxiety and appears to exhibit some anxiolytic effects. This means that it reduces experiences of anxiousness. Some evidence suggests that use of oral Gotu Kola supplements may decrease the Acoustic Startle Response (ASR), in healthy people. This startle response has been validated as a test of anxiety levels. Centella is said to induce calming, relaxing, slightly-sedative effects. More research is needed to determine whether this supplement is effective for alleviating anxiety in clinical settings. Several studies have confirmed the anti-anxiety effect of Gotu Kola.

Take 50 mg of Gotu Kola extract two times a day as a single dosage for two weeks (14 days). In the case of extreme anxiety, it is advised to take up to 2000 mg per day.

Depression:

Depression is another mental disorder that can be treated with Gotu Kola. This herb can positively affect our brains, making them function properly; thus, it is a great antidepressant. If a person suffers depression then it has adverse effects in daily life. Gotu Kola can be used to treat depression. Because it has anti-depressant properties that can treat depression. Disorders such as anger, anger, frustration, irritability, restlessness, etc. can be used by using it. The triterpenes present in the plant Centella asiatica pose antidepressant effects. Studies done on the animal model suggested that the triterpene helps in creating a momentous diminution in corticosterone level and a notable increase in the amount of monoamine-related neurotransmitters.

Take 500 mg of Gotu kola as a single dose twice a day for 2 weeks.

Sedative Properties:

The plant Gotu Kola possesses a central nervous system effect. It has tranquilizing, rejuvenating, and sedative properties along with memory-enhancing capacity due to compounds brahmoside and brahminoside.

Benefit for Nervous System:

By relieving stress, inducing sleep, and improving the mood, the Gotu Kola enhances the overall state of the nervous system. This prevents hair loss and it can also reduce the severity of epilepsy disorder if Gotu Kola is regularly taken. The herb boosts memory and grasping power. It is used as brain tonic . Its benefits in conditions like Alzheimer's disease ,anxiety and depression are also appreciated.

Nervous Disorders:

There are many health issues related to nervous disorder; such as Parkinson's disease that affects the central nervous system, Carpel tunnel syndrome, which causes numbness in the arms, paralysis, Bell's palsy, cerebral palsy, epilepsy, to name a few. These illnesses are related to the nervous system and can cause health complications. Gotu Kola has an antianxiety agent which helps in relieving stress, enhancing the mood and inducing sleep thereby calming the nervous system. The molecular mechanism of Gotu Kola on neuroprotection remains to be elucidated.

Gotu Kola has an anxiolytic activity that helps relieve stress, enhance mood, and induce sleep, thereby calming the nervous system. Calming effects of Gotu Kola that can reduce stress and stimulate healthy sleep can also calm the nervous system directly. For those who suffer from disorders like epilepsy or premature aging, it can have a powerful effect on the quality of life and the severity of the conditions if taken regularly.

Regeneration of Nervous Tissue:

Asiatic acid present in the leaves of Centella asiatica helps in the regeneration and enhancement of nervous tissue as per studies were done on human neuroblastoma cells. Therefore, enhances the learning memory.

Mental Health:

If there was one plant that could reduce signs of anxiety and depression, you'd probably take it, right? Well, that plant might be Gotu Kola. "The herb is thought to have anti-anxiety and antidepressant qualities".

Improves Mood:

Centella asiatica has equally powerful effects on the mind. Furthermore, enhanced signaling through GABA allows for Gotu Kola to a promote a positive mood. Stress and other negative influences from our life may put us on edge and give us unpleasant feelings of nervousness. Gotu Kola extract may help smooth out this edge, allowing us to enjoy our life, and not worry about all the insignificant negative things that may be happening around us on a daily basis. It also may help increase our patience during periods of heightened irritability which can help us stay happy and focused on the important tasks at hand.

Aids in Meditation:

Gotu Kola herb as a meditation aid. It balances the right and left hemispheres of the brain. This balance helps the nervous system function without any blockages and improves cognitive abilities. Since it enhances spirituality, they call it the "enlightenment herb".

Spiritual Wellbeing:

It is said to develop the crown chakra, which is the key energy centre at the top of the head, and balance the right and left hemispheres of the brain, which the leaf is said to resemble. Moreover, it possesses antidepressant properties and naturally calms nerves, inhibits anxiety, promotes better sleep and helps treat depression.

There is a large overlap between the stress regulation and mood support effects of Gotu Kola as it relates to sleep. This is largely due to the fact that a lot of these factors rely on GABA signaling. GABA is one of the main neurotransmitters responsible for slowing down brain activity which allows for efficient sleep-onset. Since Gotu Kola can help positively enhance GABA signaling in the brain, Gotu Kola extract may help us wind down at night, thus allowing us to fall asleep faster. We cover the sleep benefits of Gotu Kola in more detail in our blog about sleep.

Getting adequate sleep is one of the best things you can do for your brain. Gotu Kola has been used as a natural sleep aid for thousands of years. Researchers have found that one bad night of sleep can impair your mental faculties as much as being drunk. Chronic insomnia is a common modern malady, but the usual solution, sleep medication, is a bad idea since it robs you of restorative sleep and can cause significant memory loss.

​Induces Sleep:

Due to the anxiolytic effect of Centella asiatica, it is also claimed to have a powerful impact in treating sleep disorders. Considering it was herbal, it has minimal side effects on the neural functioning of your body. Its ability to soothe your nerve helps in inducing sleep and can be an effective treatment of insomnia. Gotu Kola is a natural remedy that is safe to use and improves sleep. In Thai medicine, this herb is traditionally ingested for centuries as a tea with honey to produce a calming effect, thus improving sleep.

Insomnia:

Good quality sleep is essential for brain health. Lack of sleep can result in memory loss, mental illness, affect concentration, and attention. So, sleep disorders like insomnia have to be taken seriously and treated immediately. Insomnia is generally caused by stress, anxiety, and depression. Some people take sleeping pills and chemical remedies, though it offers a quick result, it is not good for their health because regular sleeping pills can affect memory power.

Gotu Kola is also suggested as a herbal remedy to treat insomnia that sometimes accompanies anxiety, stress, and depression. Proponents of this herbal remedy consider it a safer alternative to prescription medications used to treat insomnia and other sleep disorders. But consult a doctor before trying this herb. Even a few research claims that Gotu Kola helps treat sleep disorders.

Having the problems of insomnia and sleeplessness, it is effective in using this herb. Gotu Kola revives powers by re-establishing mental energy. This relieves your insomnia. For this, take 3 grams of Gotu Kola powder with milk before sleeping. 1 ½ teaspoon of Centella asiatica leaves boiled with water filter and drink it before bed. Traditionally, Gotu Kola tea is sweetened with a little honey as an Ayurvedic remedy for insomnia. Take 300 to 680 mg of Gotu Kola extract thrice a day for two weeks as a single dose.

Gotu Kola acts as a GABAa antagonist and inhibits the central cholinergic action. Gotu Kola also strengthening of the mucosal defensive factors. This herb increases body fire or agni. Hence its preparations are used in Indigestion, loss of appetite, conditions like Irritable Bowel Syndrome (IBS) and amoebiasis.

Gut Health:

Gotu Kola possesses the noteworthy quality of being able to regulate digestion as it is loaded with proteins and vitamin C. It can also promote mucous secretions in the intestines which can help combat the increased acidity in severe gastric ulcers and effectively heal stomach aches.

Stomach Upset:

Traditional medicine used Gotu Kola leaves to treat severe pain in the stomach, which we now link to gastric ulcers. This treatment is still considered practical, and the anti-inflammatory and antioxidant properties of the leaves can visibly improve the health of the gut and colon.

Digestive Disorders:

Centella asiatica and its triterpenoids also have therapeutic effects on digestive disorders, which is mainly reflected by improved liver fibrosis, colitis, and gastric mucosal damage; and even reduced Helicobacter pylori gastric colonization.

Gastric Ulcer:

Centella asiatica extracts help in the inhibition of gastric ulcers. A stomach ulcer can be reduced and healed because of the asiaticoside that can be gained from Gotu Kola. This component benefits the body by acting as an anti-gastric ulcer drug. The antioxidant and anti-inflammatory properties that are found in the leaves of Gotu Kola benefits the by reinforcing the health of the gut and colon. It increases cell healing and reduces ulcers. The plants help in protecting and strengthening the mucosal barrier of the gastric tract thus protects from oxidative damage. The anti-ulcerogenic activity of fresh juice of Centella asiatica is mainly because it increases the GABA level of the brain. The healing efficiency and anti-inflammatory efficiency of the extract also help in protecting against ulcers.

Fresh juice extract of Gotu Kola has shown protection against aspirin- and ethanol-induced gastric ulcers with increased gastric mucin secretion and mucosal cell glycoprotein production. 

Detox the Body:

Recent studies are working on Gotu kola’s effect on toxicity in the kidney and liver.

Take 30 to 60 mg Gotu Kola water extract thrice a day as a single dose for two weeks.

Chronic and Recurrent Liver Injuries:

Chronic and recurrent liver injuries are often accompanied by inflammatory reactions and often develop into liver fibrosis. Therefore, treating chronic and uncontrolled inflammation is a strategy to prevent liver injury and fibrosis. The pathological mechanism of gastric mucosal injury is complex, and nonsteroidal anti-inflammatory drugs are relatively common causes. Prostaglandin biosynthesis is one of the basic components that maintain the integrity of gastric mucosa, and cyclooxygenase is essential in the process of prostaglandin synthesis. The malondialdehyde level can reflect the ROS level. Therefore, an oxidative stress response is also crucial in the process of gastric mucosal injury. The present study found that the Centella asiatica extract effectively ameliorated the drug-induced liver toxicity, improved gastric mucosal injury, and reduced H. pylori infection. The mechanisms involved were as follows: the reduction of related inflammation factors (IL−1β ↓, IL−2 ↓, IL−6 ↓, IL−10 ↓, IL−12 ↓, and TNF−α ↓) and the increase in the level of antioxidant stress factors (SOD ↑, CAT ↑, and GPx ↑). Furthermore, evidence showed that Centella asiatica could also reduce malondialdehyde and COX-2 levels, thereby ameliorating gastric mucosal damage. The pharmacological effect of asiatic acid is mainly reflected in the improvement in liver fibrosis and acute pancreatitis. It also has a certain therapeutic effect on gastrointestinal tumors.

Diuretic:

Detoxification is very important, especially these days since we are exposed to tons of toxins in the environment, even through the food and water we consume to survive! herbs like Gotu Kola help cleanse the body and boost health. Gotu kola is a mild diuretic. It helps the body flush out excess salts, toxins, and fats though urination. This helps the kidneys get rid of unwanted matter very quickly and easily.

Gotu Kola has long been known as a mild diuretic and can, thus, stimulate the release of excess toxins, salts, water, and even fat from the body through urination. This release helps to ease tension on the kidneys and generally remove toxins quickly while keeping our energy up and our fluid balances even.

Enhances Sex Drive:

There is even some traditional proof showing that Gotu Kola is used for an energetic boost in the bedroom. Increasing libido is often a side effect of other herbal remedies, and Gotu Kola is no exception. In addition to eliminating mental fatigue and increasing energy stores in the body, Gotu Kola can also bring some fire back to your relationship. These can help improve the sexual relationship between couples.

Increases Libido:

Take some dried Centella asiatica leaves, make it powder to mix with ¼ teaspoon of honey or mixed with cow milk taken two times a day. It will be increased.

Drink Gotu Kola powder mixed with fresh milk twice a day every morning and afternoon for three days once the menstruation is completed. The drink also treats dysmenorrheal. The cleansing properties of Gotu Kola benefit women with smooth skin, youthful look, proper blood circulation, and prevent diseases.

Pelvic Inflammatory Disease (PID):

Pelvic Inflammatory Disease (PID) is a microbial infection of the upper reproductive tract. Its major complications are infertility, chronic pelvic pain, rupture of a renal tubular ovarian abscess, and ectopic pregnancy. Western medicine uses antibiotics to effectively control the symptoms. However, no conclusive evidence indicated that antibiotic treatment for the pelvic inflammatory disease was safer or more effective than other methods. Asiatic acid can efficaciously treat pelvic inflammation. Asiatic acid has potential therapeutic effects on endometriosis and ovarian cancer.

Endometriosis:

Endometriosis is a common inflammatory disease often accompanied by pelvic pain and infertility. Generally, surgeries are conducted to treat endometriosis, but accumulating evidence suggest the use of plant-based drugs for the treatment, and these medicines usually alleviate the symptoms via their anti-inflammatory, anti-oxidant, anti-proliferation, and anti-apoptotic effects.

Therefore, this study concluded that the therapeutic effect of Centella asiatica on the gynecological diseases mainly reflected in the improvement in inflammation. The main research component was asiatic acid, which worked by affecting apoptosis, reducing the production of inflammatory factors and influencing the cell cycle progression. Therefore, asiatic acid may be a potential agent in the treatment of gynecological diseases, and further clinical trials are needed to verify its efficacy.

Spermatogenesis:

Gotu Kola comprises profuse volumes of the antioxidant asiatic acid and its derivatives. This provides neuroprotective effects to cells in the brain, advancing memory and learning. It also helps in slowing down the progression of Alzheimer’s and dementia, in older people affected by the disease. The antioxidants present in the herb stimulate the neural pathways and have a positive effect on the circulatory system which promotes cognitive functions. Gotu Kola extract has a positive impact on the circulatory system, thus oxygenating more of the brain and allowing cognition to improve. Also, due to the antioxidant effects of this herb, it can stimulate neural pathways by eliminating plaque and free radicals from the brain. It has been found that Centella asiatica extract, along with folic acid, has a very positive impact on brain activity and boosts cognitive functions. It improves your memory power. This has also made it a popular supplement for aging populations. The researchers suggest that Gotu Kola extract may have efficacy in preventing cognitive deficits and reducing oxidative stress. Studies in both animals and human participants have found the benefits of Gotu Kola extract in boosting cognitive function.

Not all studies have found positive results. Preliminary clinical research suggests that using a combination supplement containing Gotu Kola, Docosahexaenoic Acid (DHA), and Ginkgo biloba does not improve any marker of cognitive function, relative to placebo controls, in cognitively-intact elderly adults. More clinical research is needed to determine the therapeutic efficacy of Gotu Kola for cognitive function and disease. According to one review of studies, Gotu Kola may help support the functioning of the brain and nervous system, improve memory, and protect against aging. However, more recent studies do not support some of these claims.

Take 750 to 1000 mg of Gotu Kola at a time in a day for two weeks (14 days). Another combination supplement contains 160mg Ginkgo biloba, 68mg Gotu Kola, and 180mg decosahexaenoic acid (DHA). This supplement was taken for 4 months without producing a significant benefit for cognitive function. Some users report that Centella asiatica has a time delay before its cognitive-enhancing effects may be noticed. According to anecdotal user reviews, the effects begin to be noticeable after about 2 weeks of usage.

Improvement of Learning Disability:

Sharpens Memory:

Does Gotu Kola helps in boosting your grey matter? Gotu Kola is also popular as brain food. It enhances or improves your memory. When the aqueous extract of the whole plant is consumed, it enhances memory retention and learning and reduces the lipid peroxidation and growth of endogenous antioxidant enzymes in the brain. Gotu Kola extract has been used to treat Alzheimer's, a cognitive disorder and memory impairment disease.

Gotu Kola may regulate the activity of neurotransmitters known as Gamma-Aminobutyric Acid (GABA).2 Asiatic acid is the compound in Gotu Kola believed to trigger this effect. By influencing how GABA is absorbed by the brain, asiatic acid may be able to relieve anxiety without the sedative effect of traditional GABA agonist drugs like Ambien (zolpidem) and barbiturates. It may also play a role in treating depression, insomnia, and chronic fatigue.

Gotu Kola has long been used as an herbal tonic to treat mood disorders and enhance memory. Although research results are mixed, there is evidence of some direct and indirect benefits. In traditional medicine, Gotu Kola has been used as a natural tonic and antidote to enhance memory and treat mood swings or disorders. The herb is long used in Ayurvedic to treat mental and cognitive disorders. Gotu Kola also helps in stimulating your brain’s neural pathways by eliminating plaque and free radicals from the brain. In Indian Ayurvedic medicine, it has traditionally been used to improve memory.

What this all means is that Gotu Kola helps support overall cognitive health. This allows us to not only learn more but to also learn more efficiently. Long term supplementation of Gotu Kola extract may help us absorb school work faster and help us to pick up and solidify new skills in the work environment more readily. Based on many studies and research, Gotu Kola is possible to affect memory and cognition indirectly. Relief from anxiety and mental fatigue and more alertness undoubtedly improve the working memory of a person. Scientifically, a person with calmness and reduced anxiety experience better memory power, information processing, focusing, and concentration.

Gotu Kola has been prescribed for improving memory for centuries. Centella leaves are shadow dried and powdered. The best way to consume Gotu Kola for memory is in the form of powder. You can either buy it from the markets or make your own. Since Gotu Kola is very very famous, most of the reputed companies manufacture Gotu Kola powder so getting good quality Gotu Kola powder is not a problem at all. But if you want to make it at home, you can easily make it within a day or two. Gotu Kola powder is made by steaming the fresh leaves and always cows milk is used to steam the leaves. To make the powder, collect fresh Gotu Kola leaves and clean them well. Now take a double boiler and fill the bottom part with milk. Spread a white cotton cloth on the idli steamer and spread the leaves on top of the cloth. Close with a lid and steam till it is cooked, once it is cooked, remove and spread it on a thin dry muslin cloth and shade dry till crisp. Once crisp, powder and store. The whole process should be done in a very low flame else the milk will boil over. To use, take around half tsp of Gotu Kola powder and mix it with a cup of sweetened milk. Make sure to dry the Gotu Kola leaves well else the powder will spoil faster.

Taking one teaspoon of this powder with honey twice in a day will boost the memory power. Dry the Centella asiatita leaves with Cumin seeds, Turmeric powder and grind it together. Taking 2 grams of this powder three times a day before food with hot milk will boost memory power.

Spatial Working Memory:

Alzheimer’s Diseases:

Alzheimer’s is known as a disorder related to brain health. It is a dementing neurodegenerative disease of old age. Oral administration of Centella asiatica extracts helps in the prevention or slowing down of these diseases. The plant mainly involves reducing oxidative stress, prevents beta-amyloid plaque formation, dopamine neurotoxicity, and enzyme inhibition. Gotu Kola can enhance mood and cognition in both healthy seniors and those with Alzheimer’s disease. Alzheimer’s patients have significantly reduced levels of acetylcholine, a neurotransmitter strongly associated with memory and learning. Alzheimer’s drugs like Aricept work by blocking the breakdown of acetylcholine. Gotu Kola can effectively improve memory and enhance nerve functions. These characteristics of Gotu Kola make it a potential medicine for treating Alzheimer’s disease. The brain activity boosting the property of Centella aasiatica also has a potential effect on the treatment of this disease. Triterpenes, steroid precursors found in Gotu Kola, are beneficial for Alzheimer’s in two ways. Much like aricept, these compounds inhibit the breakdown of acetylcholine. They also prevent the formation of amyloid plaques that accumulate in the brains of people with Alzheimer’s disease.

Though there has not been enough study on the impact of Centella asiatica on human brains, a study done on mice with Alzheimer's disease showed it has a positive effect on their behavior. It might influence the plaque associated with Alzheimer's and can also protect the brain cells.

However, there is insufficient research to determine how exactly Gotu Kola can be added to the treatment of Alzheimer’s disease. If you planned to add it to your treatment, consult with your doctor first. Take 30 to 60 drops of Gotu Kola water extract 3 times a day. Always check the dosage mentioned in the bottle as it may vary between different companies.

Parkinson's Diseases:

It is also a neurodegenerative disorder associated with the degeneration of dopaminergic neurons. Studies done on animal model shows a marked decrease of degeneration of neurons due to asiaticoside dose of Centella asiatica. It protects dopaminergic neurons by opposing MPTP (1- Methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and improve locomotor dysfunction.

Epilepsy:

The extracts of Centella asiatica helps in the treatment of epileptic seizures. This is mainly because of the anticonvulsant and neuroprotective activity of the plant. Triterpenoid glycosidic compounds of Centella asiatica helps in increasing the cerebral level of GABA thus used in the treatment of epilepsy because of its anxiolytic and anticonvulsant properties.

Gotu Kola has followed multiple mechanisms of actions on brain and neurological tissues to provide different therapeutic benefits. Cholecystokinin (CCKB) receptors bind with the peptide hormones cholecystokinin (CCK) or gastrin and regulate brain and GI tract functioning. Total triterpenes present in Gotu Kola improves the hypothalamic-pituitary-adrenal axis and increase the amount of monoamine neurotransmitters contents, which elevate mood.

Improves Brain Function:

Our brain cells are often affected by neurotoxins such as arsenic, aluminum, lead, and monosodium glutamate, which are the reason for mood disorders, mental fatigue, migraines, and brain fog. The anti-oxidant property of Gotu Kola reduces the effect of these neurotoxins. The hern neutralizes the toxins and protects our brain cells from damage. Gotu Kola effectively increases the development of new brain cells. It stimulates the Brain-derived Neurotrophic Factor (BDNF) to release, a protein that has essential play in neurogenesis. BDNF improves and strengthens existing brain cells and improves the growth of new brain cells. The herb boost plasticity in the brain enhances the branching of dendrite and improves brain cell communication. In this way, It takes a few weeks for Gotu Kola’s effects to kick in and it seems to work by encouraging dendrite branching, increasing brain plasticity, and facilitating communication between brain cells. Gotu Kola also increases Nerve Growth Factor (NGF), a protein which stimulates the growth of new nerve cells and safeguards existing ones. It is hypothesized that Centella asiatica may work by increasing how far neuronal dendrites reach in the brain. It does not seem to have any effect on the number of neurons present. Researchers think that administration of this herb extends dendrite reach by activating Mitogen-Activated Protein Kinases (MAPKs). MAPK activation increases release of BDNF (brain-derived neurotrophic factor), a growth factor that increases nerve cell growth. Several studies have attempted to examine the effects of this plant for cognitive function without producing definitive results. It is sometimes used in combination with other Ayurvedic herbs, which also contains Bacopa monneria, Gingko biloba, Cat’s claw, and Rosemary extract.

Vitamin E is known mostly as a heart-healthy vitamin, but it’s equally important for your brain. Vitamin E and C are combined to prevent cognitive decline due to aging. It also improves memory, cognitive functions, and effectively reduces the risk of Alzheimer’s and dementia diseases. Vitamin E supplements with Gotu Kola is an incredible anti-oxidant and supplement for brain health. This fat-soluble vitamin slows down age-related mental decline, particularly when paired with vitamin C. When taken together, “E + C” is linked to memory improvement and a reduced risk for Alzheimer’s and dementia. Gotu Kola shows similar synergistic effects with vitamin E, making “E + Gotu Kola” another powerful brain-enhancing combination.

It is used as a memory enhancer and also brain tonic. It helps to energies your brain cells and nerves. The leaves of this plant may be taken for the development of the brain. Powdered leaves along with cow’s milk are given for mental weakness and to improve memory. Because of its great significance as Ayurvedic medicine for the brain, sometimes, it is regarded as a brain food. It is also used to improve memory. It is beneficial for the mental ability of mentally retarded children. To a greater extent, it impacts the circulatory system thus more oxygen flow to the brain and promotes cognition. The antioxidant properties ensure the breaking of plaque in the brain.

Some studies have shown Gotu Kola extracts to have some potential as an antidepressant, antiepileptic, and can help revitalize the brain. However, most of these studies have only been conducted on rats so more studies on the benefits of Gotu Kola for humans need to be done to better understand it medical potential for the brain. Despite this, the current information that we have regarding Gotu Kola seems promising. The chemical compounds contained inside the plant have, indeed, shown that it can help with depression, epilepsy, as well as improve brain function. Gotu Kola is one of the most important rejuvenating herbs for nerve and brain cells and is capable of increasing intelligence, longevity and memory.

Central Nervous System:

Gotu kola is recommended for reducing mental stress, improving memory power in the elderly, and boosting concentration. Asiaticoside in Gotu kola protects the neural cells from beta-amyloid toxicity and shows effective recovery in Alzheimer’s patients. The herb can relax the mind and aid several nervous disorders like stroke, senility, ADD, and epilepsy.

Ayurveda recommends the Gotu Kola herb as a Medhya rasayana (rejuvenative) for memory, concentration, alertness, and clarity. Its roots and leaves have the ability to help improve neurotransmitter functioning. This plant also offers neuroprotective benefits.

Daytime Fatigue:

By taking Centella asiatica prepared as Gotu Kola leaves with Onion, Garlic, and Pepper for 48 days will cure the fatigue and helps you to come out of memory loss.

Prevent Neurodegeneration:

The plant Gotu Kola helps in enhancing the cognitive effects. These compounds help in repairing and restoration of damaged neurons and improve nerve impulse transmission. The main compound of Centella asiatica that repairs the brain cells are triterpene saponosides. Therefore the extracts of this plant help in the protection of neurological related disorders and enhance memory. Most plants have some antioxidant capacity, but gotu kola excels as a neuroprotective antioxidant. Gotu Kola protects the brain from damage incurred by the assaults of everyday life.

Studies show that Gotu Kola protects the brain from neurotoxins like lead, arsenic, aluminum, and glutamate. Glutamate is an important neurotransmitter, but, in excess, it actually kills brain cells. Glutamate is also found in some foods, especially those that contain added Monosodium Glutamate (MSG).

Neuroprotective:

The plant’s anti-inflammatory properties can help reduce pain and swelling and pain due to inflammation, heal wounds, fight infection, and speed up the process of healing. This occurs because of saponins and other organic compounds that can be found in Gotu Kola.

Joint Pain:

The antioxidants in Gotu Kola, flavonoids and carotenoids, remove toxins from the body, while its high calcium content fortifies bones. This Ayurvedic herb also supplies valuable anti-inflammatory effects to swollen, painful joints, hence efficiently reducing discomfort in ailments such as arthritis. Because of the presence of anti-inflammatory properties of Gotu Kola, it helps in relieving from joint pain. Research had shown that when Gotu Kola was administered orally it suppressed joint inflammation and can help improve collagen production in the body. It can act as an effective remedy for joint pain. The herb is also shown to reduce cartilage erosion and bone erosion.

Arthritis Pain:

Gotu Kola inhibits Nitric Oxide (NO) synthesis to reduce inflammation. Madecassoside, an active phytochemical present in Gotu Kola and effective to suppress action type II collagen-induced arthritis to reduce pain and inflammation associated with arthritis. Gotu Kola is a powerful anti-inflammatory and helps provide relief for those suffering from joint pain related to problems like arthritis. It’s supposed to improve joint function and relieve common arthritis symptoms.

In 2003, Sydney, a documentary was broadcasted that showed many Australian arthritis patients were cured by having two pennywort leaves a day. Mr. Russ Maslen, an arthritis and paradoxical pennywort author, helped his wife Beryl to get out of arthritis in her hand joints completely. In his book, he shared that he got to know the benefits of Gotu Kola for arthritis in 1989 by a farmer in Brunswick Valley when he was involved in constructing and administrating the natural reserve park.

Take 300 to 680 mg Gotu Kola extract thrice a day as a single dose for 2 weeks.

Scleroderma:

A single study of 13 women with scleroderma found that Gotu Kola decreased joint pain and skin hardening, and improved finger movement.

Type 2 diabetes mellitus is a form of diabetes characterized by high blood glucose, insulin resistance, and a weaker insulin-stimulated response in the presence of high blood glucose level. Oxidative stress is mainly caused by lipid peroxidation and has been considered as the main indicator of the pathogenesis and development of type 2 diabetes. Oxidative stress causes microvascular and macrovascular complications. In addition, the inflammation response may cause the occurrence of type 2 diabetes by inducing insulin resistance. The inflammation response is exacerbated in the presence of hyperglycemia and can, in turn, worsen hyperglycemia. Hence, targeting the inflammation pathway may be a potential strategy to prevent and control diabetes.

Shadow dry the Centella leaves and Lippia Nodiflora leaves separately and powders it. Diabetic patients can take 2 gms of equally mixed above two powders will reduce the sugar level.

Blood Sugar:

Gotu Kola is well known by the Khasis' people in helping to control blood sugar levels. The herb is steeped overnight in hot water, and the water is extracted and consumed the following day. Gotu Kola is a strong candidate for alleviating diabetic symptoms, and perhaps controlling the increase of diabetes mellitus, because of its various compounds and functions. Its extracts help in reducing the blood glucose level. Ayurvedic healers have traditionally used Centella asiatica to lower blood sugar. Research done in animals supports such use.

Diabetic Microangiopathy:

Diabetes is characterized by increased skin blood flow and decreased venous return, resulting in blood pooling from decreased venous return and increased skin blood flow.

Obesity:

Gotu Kola has anti-proliferative nature, which is beneficial in curing various types of cancer. There is growing interest in Gotu Kola as a possible anticancer/chemopreventive agent.

Cancerous Tumours:

Centella leaves with castor oil boiled for some time and applies it to the tumors to reduce the severity. Some studies using dried powder extracts have shown antitumor and cytotoxic effects against tumor cells in vitro.

Colon Cancer and Liver Cancer:

Colon cancer and primary liver cancer are common types of cancers in the digestive system. The expression of E-cadherin and vimentin is considered of high reference value in the prognosis of colon cancer. The mitochondrial morphology and the cytosolic calcium level [Ca2+] are indicators of the pathological development of hepatocellular carcinoma. Asiatic acid can also affect the expression of epithelial-mesenchymal transition marker proteins in colon cancer cells (E cadherin↑, vimentin ↓, N-cadherin↓), achieved this anti-cancer potential by regulating PI3K/Akt/mTOR/p70S6K signaling pathway. In addition, asiatic acid can induce the dissipation of mitochondrial membrane potential (MMP), ATP depletion, release of cytochrome c from mitochondria into the cytosol of HepG2 cells, which may induce the death of liver cancer cells by directly affecting mitochondrial function, it may be a potential therapeutic drug for liver cancer and colon cancer.

Based on the aforementioned evidence, it was concluded that Centella asiatica maybe can improve liver, colon and stomach related digestive disorders by reducing inflammation, ameliorating oxidative stress, and improving mitochondrial function.

Ovarian Cancer and Breast Cancer:

Ovarian cancer and breast cancer are the top two cancers in women. Surgery, radiotherapy, chemotherapy, and other treatments are often associated with various complications. Therefore, exploring new therapeutic agents is particularly important. The potential therapeutic value of asiatic acid for ovarian cancer is mainly reflected in that it can promote the apoptosis of ovarian cancer cells and inhibit the growth of ovarian cancer cells by affecting the cell cycle progression.

Radioprotective:

Gotu Kola significantly reduces radiation-induced behavioral changes.

The accumulated bronchial secretions or Kapha gets easily expectorated when this herb is used in respiratory conditions like bronchitis and asthma.It is very useful in inflammation of vocal chords. The effects of Centella asiatica on respiratory diseases is mainly reflected in its ability to improve pulmonary fibrosis, ameliorate chronic obstructive pulmonary disease, and decrease lung injury and certain anti-lung cancer effects.

Therefore, the present studies showed that the effective components of Centella asiatica on respiratory diseases were asiatic acid and asiaticoside, and the major mechanism was anti-inflammation; this was also consistent with the pathological mechanism of the aforementioned diseases. Moreover, it is worth paying close attention to the potential therapeutic effect of Centella asiatica and asiatic acid on lung cancer. Also, the mechanisms of promoting apoptosis and inhibiting differentiation of tumor cells are worthy of further exploration.

Pulmonary Fibrosis:

Pulmonary fibrosis can be induced by a variety of injuries to the lung. It is characterized by fibroblast/myofibroblast activation and excessive extracellular matrix accumulation, leading to a progressive organ dysfunction mainly including varying degrees of inflammation and fibrosis. By reducing collagen accumulation, pulmonary fibrosis can be effectively improved through TGF-β1 and NLRP3 pathways and decreasing the levels of inflammation factors.

Chronic Obstructive Pulmonary Disease (COPD):

Chronic Obstructive Pulmonary Disease is a frequently progressive inflammatory disease of the respiratory tract, alveoli, and microvasculature. The pathological mechanism of COPD is that airway epithelial cell damage triggers nonspecific inflammatory responses by releasing endogenous intracellular molecules or molecular patterns associated with danger. Impaired immune regulation may play a major role in COPD. For the treatment of COPD, it is generally recommended to use appropriate long-acting maintenance bronchodilators and inhaled corticosteroids; pulmonary rehabilitation can also relieve symptoms. However, corticosteroid treatment has certain side effects. Lung cancer is the most common cause of cancer-related mortality in the world. Different treatment methods for lung cancer are generally selected according to the stages, such as surgery, radiation therapy, molecular targeted therapy, and immunotherapy.

Acute Lung Injury (ALI):

Acute lung injury is a systemic inflammation of the lungs manifested as hypoxia, edema, and pulmonary infiltrates present in the chest cavity. Acute lung injury is characterized by epithelial and vascular permeability increased, hypercoagulation and insufficient fibrinolysis, and inflammation and immune regulation.

Cold and Asthma:

Centella asiatica extract mixed and soaked with long Pepper air-dried and powdered. For cold and fever, 1 gram of this powder mixed with honey is taken two times a day. Cleaned leaves of Centella with tea cures asthma, cold and fever.

Fever:

Grind equal amount of Centella asiatica leaves with Pepper, and Tulsi leaves and make into pills and dry and store. Take these pills during a fever helps you to recover fast.

Edema:

Take 60 to 100 mg of Gotu Kola extract thrice a day for seven days before and after the flight. You can make a cream by adding 1% Gotu Kola extract with other herbs to apply to the affected area to get rid of swelling.

Gotu Kola enhances antioxidant enzyme like glutathione level and also improve catalase levels. Along with this, a significant reduction of malondialdehyde has also found. It also showed that Gotu Kola reduces lipid peroxidation with spontaneous motor activity. Gotu Kola has also been found to have antioxidant properties. This means that extracts made from Gotu Kola could be used to prevent inflammation, and slow down damage of the cells. This also means that it has potential for use in the treatment of cancer, but more studies need to be done regarding its effectiveness.

Free Radicals:

The antioxidants of Gotu Kola benefits the body by aiding in fighting free radicals in the body, improve skin health, and enhance cognition. Gotu Kola protects the brain from the harmful effects of free radicals. Free radical damage, also known as oxidative stress, occurs when unattached oxygen molecules attack cells, in much the same way that these molecules attack metal, causing it to rust. Antioxidants neutralize damaging free radicals, rendering them harmless.

Modulation of Genotoxicity:

Extracts obtained from Centella asiatica have also been found to have a bacteriolytic effect.

Antimicrobial:

Dysentery:

The antibiotic property of Gotu Kola speeds up wound healing. It further improves blood flow and strengthens veins and capillaries. It effectively reduces fever and dysentery in children.

Gotu Kola protects our immune system from toxins. A few illnesses that Gotu Kola can treat incredibly are high blood pressure, heart failure, urinary tract infection, and venereal diseases.

Immunomodulatory:

Immunostimulant:

Disease Prevention:

It has been theorized that the potent antioxidant effects of Gotu Kola may have a positive effect on the immune system and help in reducing disease risk. In addition, Gotu Kola contains asiatic acid, which has been proven to induce apoptosis (spontaneous cell death) and inhibit cell growth activity in certain types of cancer cells, including liver, breast, skin, brain, and gastrointestinal tumor cells. Because of a few unapproved claims and exaggerated that say Gotu Kola can treat all the diseases from mental illness to cancer, the actual value and benefits of Gotu Kola in treating disease have been shrouded.

Promotes Relaxation and Alertness:

Natural healers and researchers debate whether Gotu Kola is a true adaptogen (a tonic herb that helps balance the body by supporting its ability to deal with physical and emotional stress). Tonic herbs are traditionally taken on a daily basis over a long period of time, as opposed to herbs that are only used on an as-needed basis. In any case, Gotu Kola has a long tradition of use as a tonic herb for promoting longevity, vitality, and equanimity. It was found to be one of the most useful herbs to help people feel energized, alert, and relaxed. Gotu Kola is one of the safest remedies for easing stress and anxiety. Tonic herbs are traditionally taken on a daily basis over a long period of time, as opposed to an herb that is only used as needed. In any case, Gotu Kola has a long history of usage as a tonic herb for promoting longevity, vigor, and equanimity. Folklore tells of a Chinese herbalist who lived to be more than 250 years old, because of routine use of this natural plant medicine. Legend says he retained his youthfulness and health, while outliving 23 wives, after ingesting Gotu Kola every day. Some people refer to Centella asiatica as “The Fountain of Life”.

This Ayurvedic herb is used for hair as well as for getting health benefits. It is helpful in reducing the problem of hair loss. Some studies suggest that using Gotu Kola can increase hair length and decrease their fall rate. It is used for the growth of healthy hair i.e. enhances the beauty of hair by acting on the hair follicle region. The benefits of this herb also include improving the texture of your crowning glory because it strengthens blood vessels and boosts blood circulation. This results in healthy skin and scalp. Massages with gotu kola hair oil prevent hair fall, dullness, and premature greying. This herb gives stronger, thicker, and longer hair. It helps to stop hair loss and prevents graying of hair.

Take the equal proportion of Gotu Kola juice and coconut oil. Now, boil the mixture followed by cooling it. After making it cool, massage your scalp with the mix. Massaging the scalp prevents drying of it and also enhances your mental awakening. It is good to combat stress and free radicals, which are not good for hair health.

Hair Loss:

Gotu Kola is very famous for the treatment of hair loss. This herb also acts as a platform for hair re-growth. Hair loss happens when the hair follicles become weak due to malnourishment. This herb plays a very important role in strengthening the hair follicles and nourishing the scalp. It strengthens the blood vessels in the area and allows the small hair follicles to expand.

Both internal consumption and external application of Gotu Kola is very good for promoting hair growth and for preventing hair loss. The best way to use Gotu Kola for hair externally is by applying Gotu Kola oil. Gotu Kola oil can also made at home by infusing dried leaves in cold pressed oil by heating it under sunlight. To make the oil, collect fresh Gotu Kola leaves, wash them well and sun dry them well till crisp. Now take the leaves in a glass bottle, add virgin coconut oil and heat it again under sunlight till the Gotu Kola extract is infused into the oil. This oil can be used to massage the scalp. You can also take Gotu Kola tea along with applying Gotu Kola oil on the scalp for best results. Studies suggest that its effect are greatly improved when combined with Holy Basil (Tulsi) and Amla, which is just why we have formulated all of them in a Ultra Luxuriant Hair Elixir.

In the realm of beauty, its main benefit is its ability to prevent hair loss. It stimulates microcirculation, which enables greater oxygen and nutrient intake by the follicle, thereby enriching its growth. Aside from lowering stress levels, Gotu kola also reduces free radicals, which are known to be the cause of hair loss. Just apply a mixture of Gotu Kola, Amla, Holy Basil, False Daisy, and Aloe Vera to achieve a healthier hair growth.

If you have Gotu Kola powder at home, you can make a very effective hair mask with it. To make Gotu Kola hair mask, combine fresh Aloe Vera gel along with Gotu Kola powder and mix into a paste and use it as a hair mask, this mask will prevent hair fall and treat all scalp infections.

Gotu Kola is safe for pets when given in doses appropriate for their size. In veterinary natural medicine, Gotu Kola has been showing good results when used for pets for a more natural approach. Gotu Kola has chemicals known as triterpenoids that help to reduce anxiety and stress and also helps cognitive function. Because it is high in antioxidants, this powerful herb is also used to help treat heart conditions, epilepsy, and joint disorders like arthritis (reduces muscle and joint inflammation). Another ability that Gotu Kola has is wound healing. It is high in collagen and helps to improve skin health and to soothe numerous nervous disorders. It can also be used as a tonic, which helps to balance hormones.

Gotu Kola is used in herbal supplement blends for pets:

• BK-Detox: Is a supplement that supports a healthy immune system and detoxification. Gotu Kola is included in this blend helps to improve circulation, promotes strengthening of the blood vessels, and supports detoxification of the blood.
• Felimm: Is formulated to help fight viral and bacterial infections, and promote detoxification of the lymphatic system. Gotu Kola is used in Felimm for its immune system strengthening and antioxidant properties which help the body to fight off potential infections.
• Resthyro: Has been formulated to help pets with hyperthyroidism. Resthyro supports balanced thyroid activity and can help with symptoms associated with an overactive thyroid gland. Gotu Kola a part of this blend as it helps with inflammation and balancing hormones, including thyroid hormones.
• Thyro-Up: Is a herbal formula to support pets with hypothyroidism. Thyro-up helps promote balanced thyroid activity for an underactive thyroid gland and the symptoms associated with it. Gotu Kola is part of this blend for its anti-inflammatory and hormone-balancing properties.

It is suggest using it only when formulated by veterinarians and correctly dosed for your beloved furbaby. Supplements should be vet-formulated with the help of a master herbalist.

Mosquito Culex: